Columbus Crew vs St. Louis City Prediction & Betting Tips

Recent form: two very different pictures

St. Louis City have been in excellent form across their last 20 fixtures, winning 13, drawing 6 and losing just once, with 43 goals scored against 23 conceded. That sample mixes MLS league games, US Open Cup ties and a Leagues Cup match, so it's not a pure league run, but the numbers still point to a side that's rarely losing.

Columbus Crew: 20 completed matches; St. Louis City: 20 completed matches.

Columbus Crew

20 matches

Win

40% 8 / 20

Draw

20% 4 / 20

Loss

40% 8 / 20

Scored

29

Conceded

27

Difference

+2

St. Louis City

20 matches

Win

65% 13 / 20

Draw

30% 6 / 20

Loss

5% 1 / 20

Scored

43

Conceded

23

Difference

+20

Columbus Crew's equivalent run reads very differently. Eight wins, four draws and eight losses from 20 matches, with 29 goals for and 27 against, is a much more mixed bag. They've had some eye-catching results, including wins over Mexican sides in the Leagues Cup, but the week-to-week form has been patchier than their opponents'.

On raw recent form, St. Louis City look the sharper team heading into this one.

Comparative Team Statistics: Columbus Crew vs St. Louis City

Head-to-head: Columbus have had the better of it

The two clubs have only met twice in the data we have, and Columbus Crew won both. They beat St. Louis City 2-1 in a Leagues Cup group match back in 2023, then won again 2-1 away at St. Louis in MLS play in April 2025.

That's a small sample and neither game tells us much about squads more than a year on, but it's worth noting Columbus have found a way past this opponent before, even during spells when City looked strong.

A cup tie that's hard to call

This is a US Open Cup fixture rather than a league game, and it's still almost a month away from the point this form picture was taken. Form can shift a fair bit in that time, so treat these numbers as a snapshot rather than a guarantee of how either side will turn up on the night.

Put the two threads together and you get conflicting signals: St. Louis City's broader form is much stronger, but Columbus have quietly had the upper hand in this specific match-up before. Cup football also tends to bring different team selections and intensity than league games, which adds another layer of uncertainty.